Los Angeles October 28, 2008
"The successful animal model study is important to researchers because it gives preliminary data regarding the potential of this new therapeutic approach, which may have relevance to mechanisms of Alzheimer’s in humans. These results should be viewed conservatively, however, and only as an indicator for the design of subsequent human trials and not be extrapolated as necessarily working on the human brain at this point."
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Qing, H., He, G., Ly, P.T.T., Christopher J. Fox, C.J., Staufenbiel,
M.,Cai, F., Zhang, Z., Wei, S., Sun, X., Chen, C-H., Zhou, W., Wang,
K., and ng, W. (In Press). Valproic acid inhibits Aß production,
neuritic plaque formation and behavioral deficits in Alzheimer's
Disease mouse models.
J. Exp. Med. 2008 Oct 27 10.1084/jem.20512iti2
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